William Brugge, MD

Director Pancreas Biliary Center
Mass. General Hospital
Boston, MA

Medical School: MD, Baylor College of Medicine
Residency: University of Colorado Health Sciences Center
Fellowship: University of Colorado Health Sciences Center

Blurb: Dr. Brugge’s clinical research program focuses on the early detection of gastrointestinal malignancy using advanced endoscopic techniques. Endoscopic confocal endomicroscopy is a new endoscopic technique for detecting neoplasms in the GI tract.  He also uses advanced endoscopic techniques for the detection of early pancreatic malignancy arising from cystic lesions of the pancreas. Confocal needle imaging is performed using a novel catheter placed within a EUS needle and guided into a cystic lesion. A variety of cyst fluid markers are used to enhance the diagnostic accuracy of EUS imaging alone. He has examined the accuracy of CEA and cytology in the diagnosis of mucinous cystic lesions. Currently he is investigating new molecular markers such as kRAS and GNAS.