Mayo Clinic specialists explore the factors that should make cardiologists suspect cardiac amyloidosis. Martha Grogan, M.D., director, Mayo Clinic Cardiac Amyloid Clinic, Angela Dispenzieri, M.D., Hematology, and Nandan S. Anavekar, M.B., B.Ch., Cardiovascular Medicine, discuss the importance of raising awareness of the disease among cardiologists and reinforce the crucial steps to establishing a diagnosis and treatment plan.