Kristin Stanford, PhD, could see through other research that maternal exercise benefited the health of offspring, but she and her team have now studied why those benefits exist. The Ohio State team discovered through animal study that even offspring born to sedentary mothers had lower body weight, reduced adiposity, improved metabolism, improved cardiovascular function and other benefits when the breast milk they consumed came from mothers who got regular exercise. The results persisted for more than a year past birth.
“Exercise before and during pregnancy can have several beneficial effects,” Stanford says.
“Something we’d like to continue to look at is how this works. We’re looking to isolate all the benefits of maternal exercise that can be conferred to offspring.”
we Oh, wait. A couple of publications that have shown that maternal exercise improves health of offspring s. Our question was, why? And what we want to do first was to look at the isolating effects of milk on on offspring. Health took mice that were born to secretary moms and mice that were born to exercise train moms. We basically swap the letters 48 hours after birth. And so now you've got these offspring that were born to sedentary moms. You were drinking milk from train moms and vice versa. And it was really kind of striking is that we saw that these offspring who drank only the train milk how these beneficial effects of exercise. So they had lower lower body weight reduced at a posse, t improved glucose metabolism, reduced fasting insulin and improve cardiovascular function. And those effects persisted over their life spans over 52 weeks of age. So in our mouths model, we've shown that to confirm kind of the maximal beneficial effects to offspring. The my start to exercise about two weeks prior to conception in humans being able to track their physical activity again. It's right in the midst of their first trimester after they knew they were pregnant. Exercise before and during pregnancy have been shown to have several beneficial effects, even on the mother. In terms of the amount of weight that you gain during pregnancy. How you feel during pregnancy, on effects, on pre eclampsia, on several different factors for us. I think we want to do a couple different things. One of the things we would like to look at is is really determine how this molecule works. We know that it improves whole body health, both metabolic and cardiac function in offspring. We want to know how, how it does this. And you know, could it be given thio? Older adults Thio improve their whole body. Metabolic health could have other functions in terms of health. We'd also like to go back and look, you know, if there are any other changes thio milk composition that could be regulated by exercise. We're really excited to find these data. I think they're really striking, but I wanna make sure that they're kind of isolate all the beneficial effects of maternal exercise to be conferred on toe offspring. A lot of these human locally to sack rides are not in formula. And so being able to add this back could have really beneficial effects on women who aren't able to breastfeed or babies who needle extra supplementation.
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