Matthew Stern, MD, Director, Parkinson's Disease and Movement Disorders Center at Penn Medicine, discusses Parkinson’s Disease (PD) from the perspective of the rapidly evolving understanding of neurodegenerative diseases in general. Beginning with the characteristic clinical features of Parkinson’s Syndrome, Dr. Stern’s presentation covers the natural history of PD, the markers for the disease, the value of early intervention and the intriguing findings linking hyposmia and PD risk, among other subjects.